It is a concentration of the 7 fundamental protein growth factors that are actively secreted by platelets.
It includes 3 proteins in blood known to act as cell adhesion molecules: fibrin, fibronectin and vitronectin.
It promotes healing and rapid soft and hard tissue regeneration by delivering growth factors at high concentrations to the treated site.
Platelet Growth Factors: At the time of activation, platelets release growth factors and other molecules stored in their granules, and these are part of the natural healing process. These growth factors are regeneration-promoting signaling molecules, such as PDGF, TGF, EGF, VEGF, FGF and others. All these molecules regulate the healing process, inflammation, cell proliferation, reepithelialization, angiogenesis and tissue remodeling processes.
- Osteoblast replication
- Endothelial cell endothelial cell-replication
- Fibroblast and osteoblast-replication to produce collagen, replication to produce collagen
- Enhance bone-regeneration
- Stimulate matrix-formation
- Stimulation of pericytes
- Heamostatic sealant
- Stem cell binding
- Growth factor concentration
It contains a variety of Growth Factors. These are small molecules also known as cytokines that interact with the local cells and even send signals that initiate a variety of important events such as cell division and migration.
- Platelet-derived growth factor
- Transforming growth factor beta
- Fibroblast growth factor
- Insulin-like growth factor 1
- Insulin-like growth factor 2
- Vascular endothelial growth factor
- Epidermal growth factor
- Interleukin 8
- Keratinocyte growth factor
- Connective tissue growth factor