It is a concentration of the 7 fundamental protein growth factors that are actively secreted by platelets.

It includes 3 proteins in blood known to act as cell adhesion molecules: fibrin, fibronectin and vitronectin.

It promotes healing and rapid soft and hard tissue regeneration by delivering growth factors at high concentrations to the treated site.

Platelet Growth Factors: At the time of activation, platelets release growth factors and other molecules stored in their granules, and these are part of the natural healing process. These growth factors are regeneration-promoting signaling molecules, such as PDGF, TGF, EGF, VEGF, FGF and others. All these molecules regulate the healing process, inflammation, cell proliferation, reepithelialization, angiogenesis and tissue remodeling processes.

 Biological Actions

  • Osteoblast replication
  • Endothelial cell endothelial cell-replication
  • Fibroblast and osteoblast-replication to produce collagen, replication to produce collagen
  • Enhance bone-regeneration
  • Stimulate matrix-formation
  • Stimulation of pericytes
  • Heamostatic sealant
  • Stem cell binding
  • Growth factor concentration

 Bioactive Components
It contains a variety of Growth Factors. These are small molecules also known as cytokines that interact with the local cells and even send signals that initiate a variety of important events such as cell division and migration.

  • Platelet-derived growth factor
  • Transforming growth factor beta
  • Fibroblast growth factor
  • Insulin-like growth factor 1
  • Insulin-like growth factor 2
  • Vascular endothelial growth factor
  • Epidermal growth factor
  • Interleukin 8
  • Keratinocyte growth factor
  • Connective tissue growth factor